This lab’s main line of research at present focuses on the understanding of natural selection and adaptation in humans and primates through the comparative analysis of genomes. Its purpose is to understand complex adaptations through genome-wide analyses of the footprints that natural selection has left in genomes and attempt to place selection in a functional molecular framework of molecular pathways. The Evolutionary Systems Biology Lab is studying differential adaptation among human populations, including several African populations, Roma (as compared to Romanians and Indians) and in Chimpanzees. It has launched a project with the analysis of the haploid sequences of several individuals from all known groups of Southeast Asian pygmies.

Other websites: Bertranpetit Lab

 

Principal Investigator Principal Investigator

Current members Current members

Ongoing projects Ongoing projects

Publications Publications

Nye J.; Laayouni H.; Kuhlwilm M.; Mondal M.; Marques-Bonet T.; Bertranpetit J. 2018. Selection in the Introgressed Regions of the Chimpanzee Genome. Genome biology and evolution. 10(4):1132-1138 doi: 10.1093/gbe/evy077


Mattle-Greminger M.P.; Bilgin Sonay T.; Nater A.; ...[5 authors]...; Bertranpetit J.; Marques-Bonet T.; Van Schaik C.P.; Anisimova M.; Krützen M.. Genomes reveal marked differences in the adaptive evolution between orangutan species. Genome Biology. 19(1):193 doi: 10.1186/s13059-018-1562-6


Casillas, S.; Mulet, R.; Villegas-Mirón, P.; Hervas, S.; Sanz, E.; Velasco, D.; Bertranpetit, J.; Laayouni, H.; Barbadilla, A. (2018) PopHuman: The human population genomics browser. Nucleic Acids Research. 46(D1):D1003-D1010 doi: 10.1093/nar/gkx943


Casillas S., Mulet R., Villegas-Mirón P., Hervas S., Sanz E., Velasco D., Bertranpetit J., Laayouni H., Barbadilla A. 2018. PopHuman: The human population genomics browser. Nucleic Acids Research. 46(D1):D1003-D1010 doi: 10.1093/nar/gkx943


Nater, A.Email Author;Mattle-Greminger, M.P.;Nurcahyo, A.;Nowak, M.G.;de Manuel, M.;Desai, T.;Groves, C.;Pybus, M.;Sonay, T.B.;Roos, C.;Lameira, A.R.;Wich, S.A.;Askew, J.;Davila-Ross, M.;Fredriksson, G.;de Valles, G.;Casals, F.;Prado-Martinez, J.;Goossens, B.;Verschoor, E.J.;Warren, K.S.;Singleton, I.;Marques, D.A.;Pamungkas, J.;Perwitasari-Farajallah, D.;Rianti, P.;Tuuga, A.;Gut, I.G.;Gut, M.;Orozco-terWengel, P.;van Schaik, C.P.;Bertranpetit, J.;Anisimova, M.;Scally, A.;Marques-Bonet, T.;Meijaard, E. 2017. Erratum: Morphometric, Behavioral, and Genomic Evidence for a New Orangutan Species (Current Biology (2017) 27(22) (3487–3498.e10) (S0960982217312459)(10.1016/j.cub.2017.09.047). Current Biology. 27(22):3576-3577