As its name reveals, the interests of this lab’s research are focused on the analysis of the human genome diversity with the aim of inferring the genomic and population processes that are responsible for this diversity, and outlining the population and epidemiological consequences of the human genetic variability. Its main research lines are, therefore, not only connected with human genome diversity, but also with population genetics, genome variation and disease susceptibility, and genome evolution and disease.

Lab website: Comas Lab

Principal Investigator Principal Investigator

Current members Current members

Ongoing projects Ongoing projects

Publications Publications

Colobran, R.; Franco-Jarava, C.; Martín-Nalda, A.; Baena, N.; Gabau, E.; Padilla, N.; de la Cruz, X.; Pujol-Borrell, R.; Comas, D.; Soler-Palacín, P.; Hernández-González, M. (2016). Novel Mutations Causing C5 Deficiency in Three North-African FamiliesJournal of Clinical Immunology 36(4):338-296

Sudmant, P. H.; Mallick,S.; Nelson, B. J.; [22 authors]; Comas, D.; [21 authors]; Patterson, N.; Reich, D.; Eichler, E. E. 2015. Global diversity, population stratification, and selection of human copy-number variation.  Science 349(6253).


Sonay, T. B.; Carvalho,  T.; Robinson, M.; Greminger, M.; Krützen, M.; Comas, D.; Highnam, G.; Mittelman, D.; Shar, A.J.; Marques-Bonet, T.; Wagner, A. 2015. Tandem repeat variation in human and great ape populations and its impact on gene expression divergenceGenome Research 25: 1591-1599.


Sole-Morata, N.; Bertranpetit, J.; Comas, D.; Calafell, F. 2015. Y-chromosome diversity in Catalan surname samples: insights into surname origin and frequency. European Journal of Human Genetics 23(11): 1549-1557.


Dobon, B.; Hassan, H.Y.; Laayouni, H.; Luisi, P.; Ricaño-Ponce, I.; Zhernakova, A.; Wijmenga, C.; Tahir, H.; Comas, D.; Netea, M.G.; Bertranpetit, J. 2015. The genetics of East African populations: a Nilo-Saharan component in the African genetic landscapeScientific Reports. 5.