As its name reveals, the interests of this lab’s research are focused on the analysis of the human genome diversity with the aim of inferring the genomic and population processes that are responsible for this diversity, and outlining the population and epidemiological consequences of the human genetic variability. Its main research lines are, therefore, not only connected with human genome diversity, but also with population genetics, genome variation and disease susceptibility, and genome evolution and disease.

Lab website: Comas Lab

Investigador principal Investigador principal

Miembros del grupo Miembros del grupo

Proyectos en curso Proyectos en curso

Publicaciones Publicaciones

Secolin R.; Mas-Sandoval A.;  Arauna L.; Torres F.R.; de Araujo T.K.;  Santos M.L.; Rocha C.S.;  Carvalho B.S.; Cendes F.;  Lopes-Cendes I. & Comas D. 2019. Distribution of local ancestry and evidence of adaptation in admixed populations. Scientific Reports. doi.org/10.1038/s41598-019-50362-2
 


Rabionet R.; Remesal A.; Mensa-Vilaró A.; Murías S.; Alcobendas R.; González-Roca E.; Ruiz-Ortiz E.; Antón J.; Iglesias E.; Modesto C.; Comas D.; Puig A.; Drechsel O.; Ossowski S.; Yagüe J.; Merino R.; Estivill X.; Arostegui J.I. 2019. Biallelic loss-of-function LACC1/FAMIN Mutations Presenting as Rheumatoid Factor-Negative Polyarticular Juvenile Idiopathic Arthritis. Scientific Reports. 9(1):4579 doi: 10.1038/s41598-019-40874-2

Pimenta J.; M. Lopes A.; Carracedo A.; Arenas M.; Amorim A.; Comas D. 2019. Spatially explicit analysis reveals complex human genetic gradients in the Iberian Peninsula. Scientific Reports. 7825 doi: DOI: 10.1038/s41598-019-44121-6


Lorente-Galdos B.; Lao O.; Serra-Vidal G.; Santpere G.; Fadhlaoui-Zid K.; Pimenoff V.; Soodyall H.; Zalloua P.; Marques-Bonet T.; Comas D. 2019. Whole-genome sequence analysis of a Pan African set of samples reveals archaic gene flow from an extinct basal population of modern humans into sub-Saharan populations.. Genome Biology. 20(1):77. doi: 10.1186/s13059-019-1684-5

Font-Porterias N.; Arauna L.; Poveda A.; Bianco E.; Rebato E.; Prata M.J.; Calafell F.; Comas D. 2019. European Roma groups show complex West Eurasian admixture footprints and a common South Asian genetic origin. Plos Genetics. doi.org/10.1371/journal.pgen.1008417