Principal Investigator: Carles Lalueza-Fox Principal Investigator: Carles Lalueza-Fox

 

Research lines Research lines

Our research group focuses on paleogenomics -the study of structure, function and organization of ancestral genomes. We are interested in different evolutionary problems that can be answered with ancient DNA data, involving human evolution, population dynamics and diversity, as well as adaptive processes and past migrations. We work on Neanderthal remains from the site of El Sidrón in Asturias (Spain). We are also investigating the evolutionary dynamics of the prehistory of Europe through the analysis of Mesolithic, Neolithic, Copper and Bronze Age human genomes. We are also interested in the history of pathogens, and we are currently studying ancient malaria in Europe.

 

Neandertal genomic diversity

We are working on the remains from the El Sidrón site in Asturias, Spain. This is a family group of at least 13 Neandertal individuals that became accidentally accumulated in a single, synchronic event within a subterranean karstic system. El Sidrón offers the unique opportunity of launching for understanding the behaviour, diversity and kinship relationships within a contemporaneous Neandertal social group.

 

European prehistory

We are interested in reconstructing the main cultural horizons and evolutionary shifts of European prehistory by analysing past human genomes from different periods, including the Mesolithic-Neolithic transition and later periods such as the Copper and Bronze Age. We are also analysing Bell-Beaker Iberian samples for reconstructing the dynamics and nature of the expansion of the archaeological horizon and its role in the shaping of modern European genetic diversity. In addition, we are analysing ancient samples from different periods to create an Iberian genomic transect.

 

Ancient pathogens

We are reconstructing the adaptive effect of the eradicated malaria pathogens in Europe. We have retrieved Plasmodium DNA from antique microscopy slides from the Ebro Delta and we are planning to analyse also ancient human remains with potential signs of malaria.

 

Lab website: Paleogenomics Lab

News News

Principal Investigator Principal Investigator

Current members Current members

Publications since 2011 Publications since 2011

Rosas, A.; Ríos, L.; Estalrrich, A.; Liversidge, H.; García-Tabernero, A.; Huguet, R.; Cardoso, H.; Bastir, M.; Lalueza-Fox, C.; de la Rasilla, M.; Dean, C. (2018) Response to Comment on ¿The growth pattern of Neandertals, reconstructed from a juvenile skeleton from El Sidrón (Spain). Science, 359(6380):eaar3820 doi: 10.1126/science.aar3820


Olalde, I.; Brace S.; Allentoft, M.E.; Armit, I.; Kristiansen, K.; Booth, T.; Rohland, N.; Mallick, S.; Szécsényi-Nagy, A.; Mittnik, A.; Altena, E.; Lipson, M.; Lazaridis, I.; Harper, T.K.; Patterson, N.; Broomandkhoshbacht, N.; Diekmann, Y.; Faltyskova, Z.; Fernandes, D.; Ferry, M.; Harney, E.; De Knijff, P.; Michel, M.; Oppenheimer, J.; Stewardson, K.; Barclay, A.; Alt, K.W.; Liesau, C.; Rios, P.; Blasco, C.; Miguel, J.V.; Garcia, R.M.; Fernandez, A.A.; Banffy, E.; Bernabo-Brea, M.; Billoin, D.; Bonsall, C.; Bonsall, L.; Allen, T.; Buster, L.; Carver, S.; Navarro, L.C.; Craig, O.E.; Cook, G.T.; Cunliffe, B.; Denaire, A.; Dinwiddy, K.E.; Dodwell, N.; Ernee, M.; Evans, C.; Kucharik, M.; Farre, J.F.; Fowler, C.; Gazenbeek, M.; Pena, R.G.; Haber-Uriarte, M.; Haduch, E.; Hey G.; Jowett, N.; Knowles, T.; Massy, K.; Pfrengle, S.; Lefranc, P.; Lemercier, O.; Lefebvre, A.; Martinez, C.H.; Olmo, V.G.; Ramirez, A.B.; Maurandi, J.L.; Majo, T.; McKinley, J.I.; McSweeney, K.; Mende, B.G.; Mod, A.; Kulcsar, G.; Kiss, V.; Czene, A.; Patay, R.; Endrodi, A.; Kohler, K.; Hajdu, T.; Szeniczey, T.; Dani J.; Bernert, Z.; Hoole, M.; Cheronet, O.; Keating, D.; Veleminsky, P.; Dobe, M.; Candilio, F.; Brown, F.; Fernandez, R.F.; Herrero-Corral, A.-M.; Tusa, S.; Carnieri, E.; Lentini, L.; Valenti, A.; Zanini, A.; Waddington, C.; Delibes, G.; Guerra-Doce, E.; Neil, B.; Brittain, M.; Luke, M.; Mortimer, R.; Desideri, J.; Besse, M.; Brucken, G.; Furmanek, M.; Hauszko, A.; Mackiewicz, M.; Rapinski, A.; Leach, S.; Soriano, I.; Lillios, K.T.; Cardoso, J.L.; Pearson, M.P.; Wodarczak, P.; Price, T.D.; Prieto, P.; Rey, P.-J.; Risch, R.; Guerra, M.A.R.; Schmitt, A.; Serralongue, J.; Silva, A.M.; Smrcka, V.; Vergnaud, L.; Zilhao, J.; Caramelli, D.; Higham, T.; Thomas, M.G.; Kennett, D.J.; Fokkens, H.; Heyd, V.; Sheridan, A.; Sjogren, K.-G.; Stockhammer, P.W.; Krause, J.; Pinhasi, R.; Haak, W.; Barnes, I.; Lalueza-Fox, C.; Reich, D. (2018) The Beaker phenomenon and the genomic transformation of northwest EuropeNature. 555(7695):190-196 doi: 10.1038/nature25738

Weyrich LS; Duchene S; Soubrier J; Arriola L; Llamas B; Breen J; Morris AG; Alt KW; Caramelli D; Dresely V; Farrell M; Farrer AG; Francken M; Gully N; Haak W; Hardy K; Harvati K; Held P; Holmes EC; Kaidonis J; Lalueza-Fox C; de la Rasilla M; Rosas A; Semal P; Soltysiak A; Townsend G; Usai D; Wahl J; Huson DH; Dobney K; Cooper A 2017. Neanderthal behaviour, diet, and disease inferred from ancient DNA in dental calculus. Nature. 544(7650):357-361


Tassi, F.; Vai, S.; Ghirotto, S.; Lari, M.; Modi, A.; Pilli, E.; Brunelli, A.; Susca, R.R.; Budnik, A.; Labuda, D.; Alberti, F.; Lalueza-Fox, C.; Reich, D.; Caramelli, D. & Barbujani, G. Genome diversity in the Neolithic Globular Amphorae culture and the spread of Indo-European languages Proceedings of the Royal Society B, 2017 DOI: 10.1098/rspb.2017.1540

Slon, V.; Hopfe, C.; Weiß, C.L.; Mafessoni, F.; de la Rasilla, M.;  Lalueza-Fox, C.; [22 authors]; Burbano, H.A.; Pääbo, S.; Meyer, M. 2017. Neandertal and Denisovan DNA from Pleistocene sedimentsScience: in Press


Ongoing projects Ongoing projects

In the media In the media

21st - 22nd April 2018, on a research with the participation of Carles Lalueza-Fox, principal investigator at IBE:

Buscant la tomba del gran mestre dels templers, El Periódico

L’últim secret templer està ocult a la catedral de Tarragona, El País

Troben a Verona les suposades restes d'un gran mestre templer català, portal 324.cat

Aparece el cuerpo del único gran maestre templario encontrado hasta ahora, La Vanguardia

Hallados en Italia los restos de un supuesto gran maestre templario catalán, ABC

El novè gran mestre de l'orde del Temple al final del segle XII, Regió 7

Troben a Verona les suposades restes del mestre templer solsoní Arnau de Torroja, Regió 7

Hallan en Italia los restos de un gran maestre de la Orden de los Templarios nacido en España, La Sexta

La Catedral de Tarragona tiene la llave para resolver un secreto templario, Diari de Tarragona

S'han descobert les restes d'un Gran Mestre templer català?, El Nacional

Un mestre del Temple lleidatà a Itàlia, Diari Segre

Encontrados en Italia los restos de un supuesto gran maestre templario, agencia EFE

Templarios sin misterio, abc.es

Encontrados en Italia los restos de un supuesto gran maestre templario, eldiario.es

Apareció el cuerpo del único gran maestre templario encontrado hasta ahora, elcomercio.com

Misterio en un pueblo italiano: apareció el cuerpo de Arnau de Torroja, el único gran maestre templario encontrado hasta ahora, msn noticias

Hallaron en Italia los restos de un supuesto gran maestre templario, Los Andes

Un diente de un arzobispo, clave para identificar al único gran maestre templario hallado hasta ahora, La Vanguardia

 


21st March 2018: Los sapiens tuvieron al menos dos veces sexo con los misteriosos denisovanos, La Vanguardia, with comments of Carles Lalueza-Fox, principal investigator at IBE

October 2017. EFE futuroLa nueva ciencia de los genomas antiguos, article by Carles Lalueza-Fox, principal investigator of the IBE.