As its name reveals, the interests of this lab’s research are focused on the analysis of the human genome diversity with the aim of inferring the genomic and population processes that are responsible for this diversity, and outlining the population and epidemiological consequences of the human genetic variability. Its main research lines are, therefore, not only connected with human genome diversity, but also with population genetics, genome variation and disease susceptibility, and genome evolution and disease.

Lab website: Comas Lab

David Comas Martínez

Comas Martínez, David
UPF University Professor
Human Genome Diversity Lab

Julen Aizpurua Iraola

Aizpurua Iraola, Julen
Predoctoral Researcher
Human Genome Diversity

Júlia Jié Cabré Romans

Cabré Romans, Júlia Jié
Master Student
Human Genome Diversity Lab

Marcel Lucas Sánchez

Lucas Sánchez, Marcel
Predoctoral Researcher
Human Genome Diversity Lab

Jose Miguel Serradell Noguera

Serradell Noguera, Jose Miguel
Predoctoral Researcher
Human Genome Diversity

Mendizabal I, Valente C, Gusmão A, Alves C, Gomes V, Goios A, Parson W, Calafell F, Alvarez L, Amorim A, Gusmão L, Comas D, Prata MJ. 2011. Reconstructing the Indian origin and dispersal of the european Roma: A maternal genetic perspective. PLoS ONE, 6(1):1-10. DOI:10.1371/journal.pone.0015988

Martínez-Cruz B, Vitalis R, Ségurel L, Austerlitz F, Georges M, Théry S, Quintana-Murci L, Hegay T, Aldashev A, Nasyrova F, Heyer E. 2011. In the heartland of Eurasia: The multilocus genetic landscape of Central Asian populations. European Journal of Human Genetics, 19(2):216-223. DOI:10.1038/ejhg.2010.153

Laayouni H, Montanucci L, Sikora M, Melé M, Dall'Olio GM, Lorente-Galdos B, McGee KM, Graffelman J, Awadalla P, Bosch E, Comas D, Navarro A, Calafell F, Casals F, Bertranpetit J. 2011. Similarity in recombination rate estimates highly correlates with genetic differentiation in humans. PLoS ONE, 6(3). DOI:10.1371/journal.pone.0017913

Henn BM, Gignoux CR, Jobin M, Granka JM, Macpherson JM, Kidd JM, Rodríguez-Botigué L, Ramachandran S, Hon L, Brisbin A, Lin AA, Underhill PA, Comas D, Kidd KK, Norman PJ, Parham P, Bustamante CD, Mountain JL, Feldman MW. 2011. Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. Proceedings of the National Academy of Sciences of the United States of America, 108(13):5154-5162. DOI:10.1073/pnas.1017511108

Haber M, Platt DE, Badro DA, Xue Y, El-Sibai M, Bonab MA, Youhanna SC, Saade S, Soria-Hernanz DF, Royyuru A, Wells RS, Tyler-Smith C, Zalloua PA; Genographic Consortium. 2011. Influences of history, geography, and religion on genetic structure: The Maronites in Lebanon. European Journal of Human Genetics, 19(3):334-340. DOI:10.1038/ejhg.2010.177

Gaieski JB, Owings AC, Vilar MG, Dulik MC, Gaieski DF, Gittelman RM, Lindo J, Gau L, Schurr TG; Genographic Consortium. 2011. Genetic ancestry and indigenous heritage in a Native American Descendant Community in Bermuda. American Journal of Physical Anthropology, 146(3):392-405. DOI:10.1002/ajpa.21588

Fadhlaoui-Zid K, Rodríguez-Botigué L, Naoui N, Benammar-Elgaaied A, Calafell F, Comas D. 2011. Mitochondrial DNA structure in North Africa reveals a genetic discontinuity in the Nile Valley. American Journal of Physical Anthropology, 145(1):107-117. DOI:10.1002/ajpa.21472

Fadhlaoui-Zid K, Martinez-Cruz B, Khodjet-El-Khil H, Mendizabal I, Benammar-Elgaaied A, Comas D. 2011. Genetic structure of Tunisian ethnic groups revealed by paternal lineages. American Journal of Physical Anthropology, 146(2):271-280. DOI:10.1002/ajpa.21581

Batini C, Ferri G, Destro-Bisol G, Brisighelli F, Luiselli D, Sánchez-Diz P, Rocha J, Simonson T, Brehm A, Montano V, Elwali NE, Spedini G, D'Amato ME, Myres N, Ebbesen P, Comas D, Capelli C. 2011. Signatures of the preagricultural peopling processes in sub-saharan africa as revealed by the phylogeography of early y chromosome lineages. Molecular Biology and Evolution, 28(9):2603-2613. DOI:10.1093/molbev/msr089

Batini C, Lopes J, Behar DM, Calafell F, Jorde LB, van der Veen L, Quintana-Murci L, Spedini G, Destro-Bisol G, Comas D. 2011. Insights into the demographic history of African pygmies from complete mitochondrial genomes. Molecular Biology and Evolution, 28(2):1099-1110. DOI:10.1093/molbev/msq294

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