This lab’s main line of research at present focuses on the understanding of natural selection and adaptation in humans and primates through the comparative analysis of genomes. Its purpose is to understand complex adaptations through genome-wide analyses of the footprints that natural selection has left in genomes and attempt to place selection in a functional molecular framework of molecular pathways. The Evolutionary Systems Biology Lab is studying differential adaptation among human populations, including several African populations, Roma (as compared to Romanians and Indians) and in Chimpanzees. It has launched a project with the analysis of the haploid sequences of several individuals from all known groups of Southeast Asian pygmies.

Other websites: Bertranpetit Lab

 

Investigador principal Investigador principal

Miembros del grupo Miembros del grupo

Proyectos en curso Proyectos en curso

Publicaciones Publicaciones

Dall’Olio, G.M.; Laayouni, H.; Luisi, P.; Sikora, M.; Montanucci, L.; Bertranpetit, J.  2012. Distribution of events of positive selection and population differentiation in a metabolic pathway: the case of asparagine N-glycosylation. BMC Evolutionary Biology 12 (1): 98. PMID: 22731960.

Casals, F.; Bertranpetit, J.  2012. Human Genetic Variation, Shared and Private. Science 337 (6090): 39-40.

Behar, D.M.; Harmant, C.; Manry, J.; [5 authors]; Bauduer, F.; Comas, D.; Quintana‑Murci, L. The Genographic Consortium [including J. Bertranpetit].  2012. The Basque Paradigm: Genetic Evidence of a Maternal Continuity in the Franco‑Cantabrian Region since Pre‑Neolithic Times. American Journal of Human Genetics 90: 486‑493.

ArunKumar, G.; Soria Hernández, D.F.; Kavitha, V.J.; [12 authors]; Smith, C.T.; Platt, D.E.; Pitchappan, R. The Genographic Consortium [including D. Comas and J. Bertranpetit].  2012. Population Differentiation of Southern Indian Male Lineages Correlates with Agricultural Expansions Predating the Caste System. PLOS ONE 7 (11).

Sikora, M.; Laayouni, H.; Menendez, C.; [3 authors]; Mihai G. Netea; Ferran Casals; Jaume Bertranpetit  2011. A Targeted Association Study of Immunity Genes and Networks Suggests Novel Associations with Placental Malaria Infection. (2011). PLoS ONE 6(9): e24996. doi:10.1371/journal.pone.0024996