This lab’s main line of research at present focuses on the understanding of natural selection and adaptation in humans and primates through the comparative analysis of genomes. Its purpose is to understand complex adaptations through genome-wide analyses of the footprints that natural selection has left in genomes and attempt to place selection in a functional molecular framework of molecular pathways. The Evolutionary Systems Biology Lab is studying differential adaptation among human populations, including several African populations, Roma (as compared to Romanians and Indians) and in Chimpanzees. It has launched a project with the analysis of the haploid sequences of several individuals from all known groups of Southeast Asian pygmies.
Other websites: Bertranpetit Lab
Utro, F.; Pybus, M.; Parida, L. 2013. Sum of parts is greater than the whole: inference of common genetic history of populations. BMC Genomics. 14 (Suppl 1):S10
Prado-Martinez, J.; Sudmant, P. H.; Kidd, J. M.;[46 authors]; Comas, D.; [12 authors]; Navarro, A.; Akey, J. M.; Bertranpetit, J.;[9 authors]; Marques-Bonet, T. 2013. Great ape genetic diversity and population history. Nature. 499 (7459):471-475
Prado-Martinez, J.; Hernando-Herraez, I.; Lorente-Galdos, B.; [20 authors]; Bertranpetit, J.; [4 authors].; Lalueza-Fox, C.; Navarro, A.; Marques-Bonet, T. 2013. The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild. BMC Genomics. 14 (1):363
Invergo, B.; Montanucci, L.; Koch, K.-W.; Bertranpetit, J.; DellOrco, D. 2013. Exploring the rate-limiting steps in visual phototransduction recovery by bottom-up kinetic modeling. Cell Communication and Signaling. 11 (1):36
Invergo, B.; Montanucci, L.; Laayouni , H.; Bertranpetit. J. 2013. A system-level, molecular evolutionary analysis of mammalian phototransduction. BMC Evolutionary Biology. 13 (1):52