The study of the structure, function and organisation of ancestral genomes are the focal points of the Paleogenomics lab. More specifically, it looks at the different evolutionary problems that can be answered with ancient DNA data, such as those involving human evolution, population dynamics and diversity, as well as adaptive processes and past migrations. This lab works with ancient modern humans and with an extinct hominin species, Neanderthals. Regarding the latter, the research carried out to date has mainly been focused on genomic diversity among Neanderthals and the individualisation of a Neanderthal family group from El Sidrón, an archaeological site in the Asturias region of northern Spain. The Paleogenomics lab is also investigating the evolutionary dynamics and past migrations in European prehistory through the analysis of Mesolithic, Neolithic, Copper Age and Bronze Age human genomes.
Lab website: Paleogenomics Lab
Sánchez-Quinto, F.; Lalueza-Fox.; C. 2015. Almost 20 years of Neanderthal palaeogenetics: adaptation, admixture, diversity, demography and extinction. Philosophical transactions B 370(1660).
Ramirez, O.; Burgos-Paz. W.; Casas, E.;[6 authors]; Lalueza-Fox, C.; Sana, M.; Perez-Enciso, M. 2015. Genome data from a sixteenth century pig illuminate modern breed relationships. Heredity 114(2): 175-184.
Olalde, I.; Schroeder, H.; Sandoval-Velasco, M.;[14 authors]; Marquès-Bonet, T.; Gilbert, M. T. P.; Lalueza-Fox, C. 2015. A Common Genetic Origin for Early Farmers from Mediterranean Cardial and Central European LBK Cultures. Molecular Biology and Evolution 32(12): 3132-3142.
Olalde, I.; Capote, J.; Del-Arco, M.; Atoche, P.; Delgado, T.; Gonzalez-Anton, R.; Pais, J.; Amills, M.; Lalueza-Fox, C.; Ramirez, O. 2015. Ancient DNA sheds light on the ancestry of pre-hispanic Canarian pigs. Genetics Selection Evolution 47(1): 40.
Mathieson, I.; Lazaridis, I.; Rohland, N.;[16 authors]; Lalueza-Fox, C.; Reich, C. 2015. Genome-wide patterns of selection in 230 ancient Eurasians. Nature advance online publication. Ahead of print.