The study of the structure, function and organisation of ancestral genomes are the focal points of the Paleogenomics lab. More specifically, it looks at the different evolutionary problems that can be answered with ancient DNA data, such as those involving human evolution, population dynamics and diversity, as well as adaptive processes and past migrations. This lab works with ancient modern humans and with an extinct hominin species, Neanderthals. Regarding the latter, the research carried out to date has mainly been focused on genomic diversity among Neanderthals and the individualisation of a Neanderthal family group from El Sidrón, an archaeological site in the Asturias region of northern Spain. The Paleogenomics lab is also investigating the evolutionary dynamics and past migrations in European prehistory through the analysis of Mesolithic, Neolithic, Copper Age and Bronze Age human genomes.
Lab website: Paleogenomics Lab
Lari, M.; Di Vicenzo, F.; Borsato, A.; [19 authors]; Lalueza-Fox, C.; Barbujani, G.; Caramelli, D.; Manzi, G. 2015. The Neanderthal in the karst: First dating, morphometric, and paleogenetic data on the fossil skeleton from Altamura (Italy). Journal of Human Evolution 82(0): 88-94.
Knapp, M.; Lalueza-Fox, C.; Hofreiter, M. 2015. Re-inventing ancient human DNA. Investigative Genetics 6(1): 1-12.
Ferrando, A.; Manuza, A.; Jordana, J.; [11 authors]; Lalueza-Fox, C.; Ramírez, O.; Amills, M. 2015. A mitochondrial analysis reveals distinct founder effect signatures in Canarian and Balearic goats. Animal Genetics 46(4): 452-456.
Sikora, M.; Carpenter, M.L.; Moreno-Estrada, A.; Henn, B.M.; Underhill, P.A.; Sánchez-Quinto, F.; [17 authors]; Cucca, F.; and Bustamante, C.D. 2014. Population Genomic Analysis of Ancient and Modern Genomes Yields New Insights into the Genetic Ancestry of the Tyrolean Iceman and the Genetic Structure of Europe. PLoS Genetics 10 (5):e1004353
Ramirez, O.; Burgos-Paz, W.; Casas, E.; Ballester, M.; Bianco, E.; Olalde, I.; Santpere, G.; Novella, V.; Gut, M.; Lalueza-Fox, C.; Sana, M.; and Perez-Enciso, M. 2014. Genome data from a sixteenth century pig illuminate modern breed relationships. Heredity 114, 175–184