The study of the structure, function and organisation of ancestral genomes are the focal points of the Paleogenomics lab. More specifically, it looks at the different evolutionary problems that can be answered with ancient DNA data, such as those involving human evolution, population dynamics and diversity, as well as adaptive processes and past migrations. This lab works with ancient modern humans and with an extinct hominin species, Neanderthals. Regarding the latter, the research carried out to date has mainly been focused on genomic diversity among Neanderthals and the individualisation of a Neanderthal family group from El Sidrón, an archaeological site in the Asturias region of northern Spain. The Paleogenomics lab is also investigating the evolutionary dynamics and past migrations in European prehistory through the analysis of Mesolithic, Neolithic, Copper Age and Bronze Age human genomes.

Lab website: Paleogenomics Lab

Investigador principal Investigador principal

Miembros del grupo Miembros del grupo

Proyectos en curso Proyectos en curso

Publicaciones Publicaciones

Olalde, I.; Allentoft, M.E.; Sanchez-Quinto, F.; [17 authors]; Marques-Bonet, T.; Navarro, A.; Willerslev, E.; Lalueza-Fox, C. 2014. Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European. Nature 507 (7491):225-228


Gómez-Sánchez, D.; Olalde, I.; Pierini, F.; Matas-Lalueza, L.; Gigli, E.; Lari, M.; Civit, S.; Lozano, M.; Vergès, J.M.; Caramelli, D.; Ramírez, O.; Lalueza-Fox, C. 2014. Mitochondrial DNA from El Mirador Cave (Atapuerca, Spain) Reveals the Heterogeneity of Chalcolithic Populations. Plos One 9 (8):e105105


Engelken, J.; Carnero-Montoro, E.; Pybus, M.; Andrews, G.K.; Lalueza-Fox, C.; Comas, D.; Sekler, I.; de la Rasilla, M.; Rosas, A.; Stoneking, M.; Valverde, M.A.; Vicente, R.; and Bosch, E. 2014. Extreme Population Differences in the Human Zinc Transporter ZIP4 (SLC39A4) Are Explained by Positive Selection in Sub-Saharan Africa. PLoS Genet. 10 (2):e1004128


Castellano, S.; Parra, G.; Sánchez-Quinto, F.A.; [13 authors]; Lalueza-Fox, C.; [11 authors]; Kelso, J.; Andrés, A.M.; Pääbo, S. 2014. Patterns of coding variation in the complete exomes of three Neandertals. Proceedings of the National Academy of Sciences. 111 (18):6666-6671


Wood, R.E.;  Higham, T. F. G.; De Torres, T.; [3 authors]; Lalueza-Fox, C.; Sanchez-Moral, S.; Canaveras, J. C.; Rosas, A.; Santamaria, D.; De la Rasilla, M. 2013. A new date for the neanderthals from el sidron cave (asturias, northern spain). Archaeometry. 55:148-158