The main goal of this lab is to understand how nutrition regulates key physiological processes in insects. Thus, its main interest lies in unravelling how the insulin receptor pathway controls reproduction, and also how insects regulate the expression of insulin-like peptides (ILPs), the putative effectors of the signalling pathway. In addition to this, the Nutritional Signals in Insects lab, in collaboration with the Insect Reproduction Lab, studies how interference RNA (RNAi) works in insects, the enzymes involved and their functions and the mechanisms of production and selection of the small interfering RNAs (siRNAs) that are generated.
Lab website: Maestro Lab
Süren-Castillo, S.; Abrisqueta, M.; Maestro, J.L. 2012. FoxO inhibits juvenile hormone biosynthesis and vitellogenin production in the German cockroach. Insect Biochemistry and Molecular Biology 42: 491-498.
Rahman, M.M.;Franch-Marro, X.;Maestro, J.L.;Martin, D.;Casali, A. 2017. Local Juvenile Hormone activity regulates gut homeostasis and tumor growth in adult Drosophila. Scientific Reports . 7:Article number: 11677