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The goal of this lab is to understand the origin of animal multicellularity from a unicellular ancestor. To this end, the genomes of animals’ closest unicellular relatives are obtained in order to perform comparative and functional genomics. Moreover, the Multicellgenome lab is working on the development of genetic tools in two close unicellular relatives of animals with the purpose of establishing them as model organisms for addressing the origin of Metazoa. This will enable the elucidation of the ancestral function of the genes involved in multicellularity and offer insight into how they were co-opted.

Lab website: Multicellgenome Lab

Investigador principal Investigador principal

Miembros del grupo Miembros del grupo

Proyectos en curso Proyectos en curso

Publicaciones Publicaciones

Parra-Acero H.; Ros-Rocher N.; Perez-Posada A.; Ko?yczkowska A.; Sánchez-Pons N.; Nakata A.; Suga H.; Najle S.R.; Ruiz-Trillo I. 2018. Transfection of Capsaspora owczarzaki, a close unicellular relative of animals. Development (Cambridge). 145(10): dev162107 doi: 10.1242/dev.162107


López-Escardó D.; Paps J.; De Vargas C.; Massana R.; Ruiz-Trillo I.; Del Campo J. 2018. Metabarcoding analysis on European coastal samples reveals new molecular metazoan diversity. Scientific Reports. 8(1):9106 doi: 10.1038/s41598-018-27509-8


López-Escardó, D.; López-García, P.; Moreira, D.; Ruiz-Trillo, I.; Torruella, G. 2018. Parvularia atlantis gen. et sp. nov., a Nucleariid Filose Amoeba (Holomycota, Opisthokonta). Eukaryotic Microbiology. 65(2):170-179 DOI: 10.1111/jeu.12450


Leonard, G.; Labarre, A.; Milner, D.S.; Monier, A.; Soanes, D.; Wideman, J.G.; Maguire, F.; Stevens, S.; Sain, D.; Grau-Bové, X.; Sebé-Pedrós, A.; Stajich, J.E.; Paszkiewicz, K.; Brown, M.W.; Hall, N.; Wickstead, B.; Richards, T.A. 2018. Comparative genomic analysis of the 'pseudofungus' Hyphochytrium catenoides. Open Biology. 8(1):170184 doi: 10.1098/rsob.170184.


Rafels-Ybern, A.; Torres, A.G.; Grau-Bove, X.; Ruiz-Trillo, I.; Ribas de Pouplana, L. 2018. Codon adaptation to tRNAs with Inosine modification at position 34 is widespread among Eukaryotes and present in two Bacterial phyla. RNA Biology, DOI: 10.1080/15476286.2017.1358348