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The goal of this lab is to understand the origin of animal multicellularity from a unicellular ancestor. To this end, the genomes of animals’ closest unicellular relatives are obtained in order to perform comparative and functional genomics. Moreover, the Multicellgenome lab is working on the development of genetic tools in two close unicellular relatives of animals with the purpose of establishing them as model organisms for addressing the origin of Metazoa. This will enable the elucidation of the ancestral function of the genes involved in multicellularity and offer insight into how they were co-opted.
Lab website: Multicellgenome Lab
Investigador principal
Miembros del grupo
Proyectos en curso
Publicaciones
Rafels-Ybern, A.; Torres, A.G.; Grau-Bove, X.; Ruiz-Trillo, I.; Ribas de Pouplana, L. 2018. Codon adaptation to tRNAs with Inosine modification at position 34 is widespread among Eukaryotes and present in two Bacterial phyla. RNA Biology, DOI: 10.1080/15476286.2017.1358348
Parra-Acero H.; Ros-Rocher N.; Perez-Posada A.; Ko?yczkowska A.; Sánchez-Pons N.; Nakata A.; Suga H.; Najle S.R.; Ruiz-Trillo I. 2018. Transfection of Capsaspora owczarzaki, a close unicellular relative of animals. Development (Cambridge). 145(10): dev162107 doi: 10.1242/dev.162107
Ondracka A.; Dudin O.; Ruiz-Trillo I. 2018. Decoupling of Nuclear Division Cycles and Cell Size during the Coenocytic Growth of the Ichthyosporean Sphaeroforma arctica. Current Biology. 28(12):1964-1969.e2 doi: 10.1016/j.cub.2018.04.074
López-Escardó D.; Paps J.; De Vargas C.; Massana R.; Ruiz-Trillo I.; Del Campo J. 2018. Metabarcoding analysis on European coastal samples reveals new molecular metazoan diversity. Scientific Reports. 8(1):9106 doi: 10.1038/s41598-018-27509-8
López-Escardó, D.; López-García, P.; Moreira, D.; Ruiz-Trillo, I.; Torruella, G. 2018. Parvularia atlantis gen. et sp. nov., a Nucleariid Filose Amoeba (Holomycota, Opisthokonta). Eukaryotic Microbiology. 65(2):170-179 DOI: 10.1111/jeu.12450