Human Population Genomics
Our research focuses on studying different aspects of human genome variation, population genetics, and disease susceptibility in the past and present Native American and Latin American populations. We develop and implement statistical methods leveraging human genetic variation to understand the different populations' evolutionary histories.
Nunes K, Castro E Silva MA, Rodrigues MR, Lemes RB, Pezo-Valderrama P, Kimura L, Sena LS, Krieger JE, Varela MC, Azevedo LO, Camargo LMA, Ferreira RGM, Krieger H, Bortolini MC, Mill JG, Sacuena P, Guerreiro JF, Souza CMB, Veronese FV, Vianna FSL, Comas D, Pereira AC, Pereira LV, Hünemeier T. 2025. Admixture's impact on Brazilian population evolution and health. Science, 388(6748):eadl3564. DOI: 10.1126/science.adl3564.
Nagai A, Lemes RB, Mill JG, Pereira AC, Marques RE, Hünemeier T. 2024. The seroconversion history to SARS-CoV-2 in Indigenous people from Brazil – the interplay between exposure, vaccination, and tuberculosis. Frontiers in Immunology, 15(July):1-9. DOI:10.3389/fimmu.2024.1359066
Hünemeier T. 2024. Biogeographic Perspectives on Our Species’ Genetic Diversification. Molecular Biology and Evolution, 41(3). DOI:10.1093/molbev/msae029
Ferraz T, Suarez Villagran X, Nägele K, Radzevičiūtė R, Barbosa Lemes R, Salazar-García DC, Wesolowski V, Lopes Alves M, Bastos M, Rapp Py-Daniel A, Pinto Lima H, Mendes Cardoso J, Estevam R, Liryo A, Guimarães GM, Figuti L, Eggers S, Plens CR, Azevedo Erler DM, Valadares Costa HA, da Silva Erler I, Koole E, Henriques G, Solari A, Martin G, Serafim Monteiro da Silva SF, Kipnis R, Müller LM, Ferreira M, Carvalho Resende J, Chim E, da Silva CA, Borella AC, Tomé T, Müller Plumm Gomes L, Barros Fonseca D, Santos da Rosa C, de Moura Saldanha JD, Costa Leite L, Cunha CMS, Viana SA, Ozorio Almeida F, Klokler D, Fernandes HLA, Talamo S, DeBlasis P, Mendonça de Souza S, de Paula Moraes C, Elias Oliveira R, Hünemeier T, Strauss A, Posth C. 2023. Genomic history of coastal societies from eastern South America. Nature Ecology & Evolution, 7(August):9-11. DOI:10.1038/s41559-023-02114-9
Fam BSO, Feira MF, Cadore NA, Sbruzzi R, Hünemeier T, Abel L, Zhang Q, Casanova JL, Vianna FSL. 2023. Human genetic determinants of COVID-19 in Brazil: challenges and future plans. Genetics and Molecular Biology, 46(3 suppl 1):1-8. DOI:10.1590/1678-4685-gmb-2023-0128
Couto-Silva CM, Nunes K, Venturini G, Araújo Castro E Silva M, Pereira LV, Comas D, Pereira A, Hünemeier T. 2023. Indigenous people from Amazon show genetic signatures of pathogen-driven selection. Science Advances, 9(10):1-10. DOI:10.1126/sciadv.abo0234
Castro e Silva MA, Hünemeier T. 2023. A multidisciplinary overview on the Tupi‐speaking people expansion. American Journal of Biological Anthropology. DOI:10.1002/ajpa.24876
Giudicelli GC, De Souza CMB, Veronese FV, Pereira L V., Hünemeier T, Vianna FSL. 2022. Precision medicine implementation challenges for APOL1 testing in chronic kidney disease in admixed populations. Frontiers in Genetics, 13(December):1-8. DOI:10.3389/fgene.2022.1016341