Throughout the Earth’s history, evolution has developed a great number of different organisms with an incredible variety of forms and sizes. These morphologies are tailored during development by modifying the expression pattern of key genes and by the modulation of hormone activation. The main goal of this lab is, therefore, to understand how changes in gene and hormone regulation affect morphology evolution, particularly in relation to the origin of insect metamorphosis. The Evolution and Developmental Biology lab addresses these questions by comparing the development and metamorphosis of Drosophila melanogasterTribolium castaneum and Thermobia domestica.

Principal Investigator Principal Investigator

Current members Current members

Ongoing projects Ongoing projects

Publications Publications

Mané-Padrós, D.; Borr.s-Castells, F.; Bellés, X.; Martín, D.  2012. Nuclear receptor HR4 plays an essential role in the ecdysteroid-triggered gene cascade in the development of the hemimetabolous insect Blattella germanica. Molecular and Cellular Endocrinology 348: 322-330.

Grillo, M.; Furriols, M.; de Miguel, C.; Franch-Marro, X.; Casanova, J.  2012. Conserved and divergent elements in Torso RTK activation in Drosophila development. Scientific Reports 2, 762; doi: 10.1038/srep00762.

Casals, F.; Sikora, M.; Laayouni, H.; [4 authors] Awadalla, P.; Netea, MG.; Bertranpetit, J. 2011. Genetic adaptation of the antibacterial human innate immunity network. BMC Evolutionary Biology 11: 202.

Capelli, C.;  Batini, C.; Ferri, G.; [11 authors]; Myres, N.; Ebbesen, P.; Comas, D. 2011. Early Y chromosome lineages in Africa: the origin and dispersal of Homo sapiensAmerican Journal of Physical Anthropology 144: 103.

Campbell, K.; Whissell, G.; Franch-Marro, X.; Batlle, E.; Casanova, J. 2011. Specific GATA Factors Act as Conserved Inducers of an Endodermal-EMTDevelopmental Cell 21: 1051-1061.

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