As its name reveals, the interests of this lab’s research are focused on the analysis of the human genome diversity with the aim of inferring the genomic and population processes that are responsible for this diversity, and outlining the population and epidemiological consequences of the human genetic variability. Its main research lines are, therefore, not only connected with human genome diversity, but also with population genetics, genome variation and disease susceptibility, and genome evolution and disease.
Lab website: Comas Lab
Principal Investigator
Current members
Ongoing projects
Publications
Sánchez-Quinto, F.; Rodríguez-Botigué, L.; Civit, S.; [3 authors];Comas, D.; Lalueza-Fox, C. 2012. North African populations carry the signature of admixture with Neandertals. PLOS ONE 7 (10): e47765.
Sánchez-Quinto, F.; Schroeder, H.; Ramírez, O.; [6 authors]; Bertranpetit, J.; Orlando, L.; Gilbert, M.T.P.; Lalueza-Fox, C. 2012. Genomic affinities of two 7,000-year-old Iberian hunter-gatherers. Current Biology 22: 1494-1499. PMID: 22748318.
Pimenoff, V.; Laval, G.; Comas, D.; Palo, J.U.; Gut, I.; Cann, H.; Excoffier, L.; Sajantilla, A. 2012. Similarity in recombination rate and linkage disequilibrium at CYP2C and CYP2D cytochrome P450 gene regions among Europeans indicates signs of selection and no advantage of using tagSNPs in population isolates. Pharmacogenetics and Genomics 22:846-857.
Mendizabal, I.; Marigorta, U.M.; Lao, O.; Comas, D. 2012. Adaptative evolution of loci covarying with the human African Pygmy phenotype. Human Genetics 131: 1305-1317.
Mendizabal, I.; Lao, O.; Marigorta, U.M.; [16 authors]; Macek, M. Jr.; Comas, D.; Kayser, M. 2012. Reconstructing population history of European Romani from genome-wide data. Current Biology 22: 2342-2349.
—
5 Items per page