As its name reveals, the interests of this lab’s research are focused on the analysis of the human genome diversity with the aim of inferring the genomic and population processes that are responsible for this diversity, and outlining the population and epidemiological consequences of the human genetic variability. Its main research lines are, therefore, not only connected with human genome diversity, but also with population genetics, genome variation and disease susceptibility, and genome evolution and disease.

Lab website: Comas Lab

Principal Investigator Principal Investigator

Current members Current members

Ongoing projects Ongoing projects

Publications Publications

Bekada, A.; Arauna, L. R.; Deba, T.; Calafell, F.; Benhamamouch, S.; Comas, D. 2015. Genetic Heterogeneity in Algerian Human Populations. Plos One 10(9): e0138453.


Solé-Morata, N.; Bertranpetit, J.; Comas, D.; and Calafell, F. 2014. Recent Radiation of R-M269 and High Y-STR Haplotype Resemblance Confirmed. Annals of Human Genetics 78 (4):253-254.


Lazaridis, I.; Patterson, N.; Mittnik, A.; [106 authors]; Comas, D.; [8 authors].; Kelso, J.; Reich, D.; Krause, J. 2014. Ancient human genomes suggest three ancestral populations for present-day Europeans. Nature. 513 (7518):409-413


Engelken, J.; Carnero-Montoro, E.; Pybus, M.; Andrews, G.K.; Lalueza-Fox, C.; Comas, D.; Sekler, I.; de la Rasilla, M.; Rosas, A.; Stoneking, M.; Valverde, M.A.; Vicente, R.; and Bosch, E. 2014. Extreme Population Differences in the Human Zinc Transporter ZIP4 (SLC39A4) Are Explained by Positive Selection in Sub-Saharan Africa. PLoS Genet. 10 (2):e1004128


Elhaik, E.; Tatarinova,T.; Chebotarev, D.; [19 authors];Comas, D.; [6 authors]; Hammer, M.; Matisoo-Smith, L.; Wells, R.S.; The Genographic, Consortium. 2014. Geographic population structure analysis of worldwide human populations infers their biogeographical origins. Nature Communications 5: 3513