Human Genome Diversity Lab
As its name reveals, the interests of this lab’s research are focused on the analysis of the human genome diversity with the aim of inferring the genomic and population processes that are responsible for this diversity, and outlining the population and epidemiological consequences of the human genetic variability. Its main research lines are, therefore, not only connected with human genome diversity, but also with population genetics, genome variation and disease susceptibility, and genome evolution and disease.
Lab website: Comas Lab
Henn BM, Gignoux CR, Jobin M, Granka JM, Macpherson JM, Kidd JM, Rodríguez-Botigué L, Ramachandran S, Hon L, Brisbin A, Lin AA, Underhill PA, Comas D, Kidd KK, Norman PJ, Parham P, Bustamante CD, Mountain JL, Feldman MW. 2011. Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. Proceedings of the National Academy of Sciences of the United States of America, 108(13):5154-5162. DOI:10.1073/pnas.1017511108
Haber M, Platt DE, Badro DA, Xue Y, El-Sibai M, Bonab MA, Youhanna SC, Saade S, Soria-Hernanz DF, Royyuru A, Wells RS, Tyler-Smith C, Zalloua PA; Genographic Consortium. 2011. Influences of history, geography, and religion on genetic structure: The Maronites in Lebanon. European Journal of Human Genetics, 19(3):334-340. DOI:10.1038/ejhg.2010.177
Gaieski JB, Owings AC, Vilar MG, Dulik MC, Gaieski DF, Gittelman RM, Lindo J, Gau L, Schurr TG; Genographic Consortium. 2011. Genetic ancestry and indigenous heritage in a Native American Descendant Community in Bermuda. American Journal of Physical Anthropology, 146(3):392-405. DOI:10.1002/ajpa.21588
Fadhlaoui-Zid K, Rodríguez-Botigué L, Naoui N, Benammar-Elgaaied A, Calafell F, Comas D. 2011. Mitochondrial DNA structure in North Africa reveals a genetic discontinuity in the Nile Valley. American Journal of Physical Anthropology, 145(1):107-117. DOI:10.1002/ajpa.21472
Fadhlaoui-Zid K, Martinez-Cruz B, Khodjet-El-Khil H, Mendizabal I, Benammar-Elgaaied A, Comas D. 2011. Genetic structure of Tunisian ethnic groups revealed by paternal lineages. American Journal of Physical Anthropology, 146(2):271-280. DOI:10.1002/ajpa.21581
Batini C, Ferri G, Destro-Bisol G, Brisighelli F, Luiselli D, Sánchez-Diz P, Rocha J, Simonson T, Brehm A, Montano V, Elwali NE, Spedini G, D'Amato ME, Myres N, Ebbesen P, Comas D, Capelli C. 2011. Signatures of the preagricultural peopling processes in sub-saharan africa as revealed by the phylogeography of early y chromosome lineages. Molecular Biology and Evolution, 28(9):2603-2613. DOI:10.1093/molbev/msr089
Batini C, Lopes J, Behar DM, Calafell F, Jorde LB, van der Veen L, Quintana-Murci L, Spedini G, Destro-Bisol G, Comas D. 2011. Insights into the demographic history of African pygmies from complete mitochondrial genomes. Molecular Biology and Evolution, 28(2):1099-1110. DOI:10.1093/molbev/msq294