Research lines Research lines

The study of the structure, function and organisation of ancestral genomes are the focal points of the Paleogenomics lab. More specifically, it looks at the different evolutionary problems that can be answered with ancient DNA data, such as those involving human evolution, population dynamics and diversity, as well as adaptive processes and past migrations. This lab works with ancient modern humans and with an extinct hominin species, Neanderthals. Regarding the latter, the research carried out to date has mainly been focused on genomic diversity among Neanderthals and the individualisation of a Neanderthal family group from El Sidrón, an archaeological site in the Asturias region of northern Spain. The Paleogenomics lab is also investigating the evolutionary dynamics and past migrations in European prehistory through the analysis of Mesolithic, Neolithic, Copper Age and Bronze Age human genomes.

Lab website: Paleogenomics Lab

Principal Investigator Principal Investigator

Current members Current members

Ongoing projects Ongoing projects

Publications Publications

Welker F.; Ramos-Madrigal J.; Kuhlwilm M....[ 9 authors]...; Liao W.; Lalueza-Fox C.; Olsen J.V.; Demeter F.; Wang W.; Marques-Bonet T.; Cappellini E. 2019. Enamel proteome shows that Gigantopithecus was an early diverging pongine. Nature.  doi:

Van Dorp L.; Gelabert P.;  Rieux A.; de Manuel M.; de-Dios T.; Gopalakrishnan S.; Carøe C.; Sandoval-Velasco M.;  Fregel R.; Olalde I.; Escosa R.; Aranda C.; Huijben S.;  Mueller I.; Marquès-Bonet T.;  Balloux F.;  P Gilbert T.; Lalueza-Fox C. 2019. Plasmodium vivax Malaria viewed through the lens of an eradicated European strain. Molecular Biology and

Ríos L.; Kivell T.L.; Lalueza-Fox C.; Estalrrich A.; García-Tabernero A.; Huguet R.; Quintino Y.; de la Rasilla M.; Rosas A. 2019. Skeletal Anomalies in The Neandertal Family of El Sidrón (Spain) Support A Role of Inbreeding in Neandertal Extinction. Scientific Reports. 9(1):1697 doi: 10.1038/s41598-019-38571-1

Olalde I.; Mallick S.; Patterson N.;…[ 106 authors]…Lalueza C.; Reich D. 2019. The genomic history of the Iberian Peninsula over the past 8000 years. science. 363, Issue 6432, pp. 1230-1234 doi: 10.1126/science.aav4040

Narasimhan V.M.; Patterson N.; Moorjan P.;…[ 105 authors]…; Lalueza-Fox C.; Meyer M.;Anthony D.;Boivin N.;Thangaraj K.;Kennett D.J.;Frachetti M.;Pinhasi R.;Reich D. 2019. The formation of human populations in South and Central Asia. Science. 365-6457 doi:10.1126/science.aat7487