Research lines Research lines

The study of the structure, function and organisation of ancestral genomes are the focal points of the Paleogenomics lab. More specifically, it looks at the different evolutionary problems that can be answered with ancient DNA data, such as those involving human evolution, population dynamics and diversity, as well as adaptive processes and past migrations. This lab works with ancient modern humans and with an extinct hominin species, Neanderthals. Regarding the latter, the research carried out to date has mainly been focused on genomic diversity among Neanderthals and the individualisation of a Neanderthal family group from El Sidrón, an archaeological site in the Asturias region of northern Spain. The Paleogenomics lab is also investigating the evolutionary dynamics and past migrations in European prehistory through the analysis of Mesolithic, Neolithic, Copper Age and Bronze Age human genomes.

Lab website: Paleogenomics Lab

Principal Investigator Principal Investigator

Current members Current members

Ongoing projects Ongoing projects

Publications Publications

Sánchez-Quinto, F.; Schroeder, H.; Ramírez, O.; [6 authors]; Bertranpetit, J.; Orlando, L.; Gilbert, M.T.P.; Lalueza-Fox, C.  2012. Genomic affinities of two 7,000-year-old Iberian hunter-gatherers. Current Biology 22: 1494-1499. PMID: 22748318.

Mannino, M.; Catalano, G.; Talamo, S.; [3 authors]; Lalueza-Fox, C.; Messina, A.; Petruso, D.; Caramelli, D.; Richards, MP.; Sineo, L.  2012. Origin and Diet of the Prehistoric Hunter-Gatherers on the Mediterranean Island of Favignana (.gadi Islands, Sicily). PLOS ONE 7 (11).

López-Valenzuela, M.; Ramírez, O.; Rosas, A.; García-Vargas, S.; Rasilla, M.; Lalueza-Fox, C.; Espinosa-Parrilla, Y.  2012. An ancestral miR-1304 allele present in Neanderthals regulates genes involved in enamel formation and could explain dental differences with modern humans. Molecular Biology and Evolution 29 (7): 1797-1806.

Lalueza-Fox, C.; Gigli, E.; Sánchez-Quinto, F.; de la Rasilla, M.; Fortea, J.; Rosas, A.  2012. Issues from Neandertal genomics: Diversity, adaptation and hybridisation revised from the El Sidrón case study. Quaternary International 247: 10-14.

Lalueza-Fox, C.; Rosas, A. de la Rasilla, M.  2012. Palaeogenetic research at El Sidrón Neandertal site. Annals of Anatomy 194 (1): 133-137.