The study of the structure, function and organisation of ancestral genomes are the focal points of the Paleogenomics lab. More specifically, it looks at the different evolutionary problems that can be answered with ancient DNA data, such as those involving human evolution, population dynamics and diversity, as well as adaptive processes and past migrations. This lab works with ancient modern humans and with an extinct hominin species, Neanderthals. Regarding the latter, the research carried out to date has mainly been focused on genomic diversity among Neanderthals and the individualisation of a Neanderthal family group from El Sidrón, an archaeological site in the Asturias region of northern Spain. The Paleogenomics lab is also investigating the evolutionary dynamics and past migrations in European prehistory through the analysis of Mesolithic, Neolithic, Copper Age and Bronze Age human genomes.
Lab website: Paleogenomics Lab
Olalde, I.; Brace S.; Allentoft, M.E.; …[138 authors]...; Barnes, I.; Lalueza-Fox, C.; Reich, D. (2018) The Beaker phenomenon and the genomic transformation of northwest Europe. Nature. 555(7695):190-196 doi: 10.1038/nature25738
Gomez-Sanchez D.; Olalde I.; Sastre N.; Enseñat C.; Carrasco R.; Marques-Bonet T.; Lalueza-Fox C.; Leonard J.A.; Vilà C.; Ramírez O. 2018. On the path to extinction: Inbreeding and admixture in a declining grey wolf population. Molecular Ecology. 27(18):3599-3612 doi: 10.1111/mec.14824
Weyrich LS; Duchene S; Soubrier J; Arriola L; Llamas B; Breen J; Morris AG; Alt KW; Caramelli D; Dresely V; Farrell M; Farrer AG; Francken M; Gully N; Haak W; Hardy K; Harvati K; Held P; Holmes EC; Kaidonis J; Lalueza-Fox C; de la Rasilla M; Rosas A; Semal P; Soltysiak A; Townsend G; Usai D; Wahl J; Huson DH; Dobney K; Cooper A 2017. Neanderthal behaviour, diet, and disease inferred from ancient DNA in dental calculus. Nature. 544(7650):357-361