Research lines Research lines

The study of the structure, function and organisation of ancestral genomes are the focal points of the Paleogenomics lab. More specifically, it looks at the different evolutionary problems that can be answered with ancient DNA data, such as those involving human evolution, population dynamics and diversity, as well as adaptive processes and past migrations. This lab works with ancient modern humans and with an extinct hominin species, Neanderthals. Regarding the latter, the research carried out to date has mainly been focused on genomic diversity among Neanderthals and the individualisation of a Neanderthal family group from El Sidrón, an archaeological site in the Asturias region of northern Spain. The Paleogenomics lab is also investigating the evolutionary dynamics and past migrations in European prehistory through the analysis of Mesolithic, Neolithic, Copper Age and Bronze Age human genomes.

Lab website: Paleogenomics Lab

Principal Investigator Principal Investigator

Current members Current members

Ongoing projects Ongoing projects

Publications Publications

Chang, D.; Knapp, M.; Enk, J.; Lippold, S.; Kircher, M.; Lister, A.; MacPhee, R.D.E.; Widga, C.; Czechowski, P.; Sommer, R.; Hodges, E.; Stümpel, N.; Barnes, I.; Dalén, L.; Derevianko, A.; Germonpré, M.; Hillebrand-Voiculescu, A.; Constantin, S.; Kuznetsova, T.; Mol, D.; Rathgeber, T.; Rosendahl, W.; Tikhonov, A.N.; Willerslev, E.; Hannon, G.; Lalueza-Fox, C.; Joger, U.; Poinar, H.; Hofreiter, M.; and Shapiro, B. 2017. The evolutionary and phylogeographic history of woolly mammoths: a comprehensive mitogenomic analysis. Scientific Reports 7: 44585

Kuhlwilm, M.; Gronau, I.; Hubisz, M.J.; de Filippo, C.; Prado-Martinez, J.; Kircher, M.; Fu, Q.; Burbano, H.A.; Lalueza-Fox, C.; de la Rasilla, M.; Rosas, A.; Rudan, P.; Brajkovic, D.; Kucan, Ž.; Gušic, I.; Marques-Bonet, T.; Andrés, A.M.; Viola, B.; Pääbo, S.; Meyer, M.; Siepel, A.; and Castellano, S. (2016). Ancient gene flow from early modern humans into Eastern NeanderthalsNature 530(7591):429-33. doi: 10.1038/nature16544.

Gelabert, P.; Sandoval-Velasco, M.; Olalde, I.; Fregel, R.; Rieux, A.; Escosa, R.; Aranda, C.; Paaijmans, K.; Mueller, I.; Gilbert, M.T.P.; Lalueza-Fox, C. (2016).Mitochondrial DNA from the eradicated European Plasmodium vivax and P. falciparum from 70-year-old slides from the Ebro Delta in SpainProceedings of the National Academy of Sciences (PNAS) doi: 10.1073/pnas.1611017113

Calafell, F.; Anglada, R.; Bonet, N.; González-Ruiz, M.; Prats-Muñoz, G.; Rasal, R.; Lalueza-Fox, C.; Bertranpetit, J.; Malgosa, A.; and Casals, F. (2016). An assessment of a massively parallel sequencing approach for the identification of individuals from mass graves of the Spanish Civil War (1936-1939)Electrophoresis [Epub ahead of print]

Vai, S.; Ghirotto, S.; Pilli, E.; [5 authors]; Lalueza-Fox, C.; [10 authors]; Geary, P.; Caramelli, D.; Barbujani, G. 2015. Genealogical Relationships between Early Medieval and Modern Inhabitants of Piedmont.  Plos One 10(1): e0116801.