Research lines Research lines

The study of the structure, function and organisation of ancestral genomes are the focal points of the Paleogenomics lab. More specifically, it looks at the different evolutionary problems that can be answered with ancient DNA data, such as those involving human evolution, population dynamics and diversity, as well as adaptive processes and past migrations. This lab works with ancient modern humans and with an extinct hominin species, Neanderthals. Regarding the latter, the research carried out to date has mainly been focused on genomic diversity among Neanderthals and the individualisation of a Neanderthal family group from El Sidrón, an archaeological site in the Asturias region of northern Spain. The Paleogenomics lab is also investigating the evolutionary dynamics and past migrations in European prehistory through the analysis of Mesolithic, Neolithic, Copper Age and Bronze Age human genomes.

Lab website: Paleogenomics Lab

Principal Investigator Principal Investigator

Current members Current members

Ongoing projects Ongoing projects

Publications Publications

Slon, V.; Hopfe, C.; Weiß, C.L.; Mafessoni, F.; de la Rasilla, M.;  Lalueza-Fox, C.; [22 authors]; Burbano, H.A.; Pääbo, S.; Meyer, M. 2017. Neandertal and Denisovan DNA from Pleistocene sedimentsScience: in Press


Slon, V.; Hopfe, C.; Weiß, C.L.; Mafessoni, F.; de la Rasilla, M.;  Lalueza-Fox, C.; Rosas, A.; Soressi, M.; Knul, M.V.; Miller, R.; Stewart, J.R.;Derevianko, A.P.; Jacobs, Z.; Li, B.; Roberts, R.G.; Shunkov, M.V.; de Lumley, H.; Perrenoud, C.; Gušić, I.; Kućan, Z.; Rudan, P.; Aximu-Petri, A.; Essel, E.; Nagel, S.; Nickel, B.; Schmidt, A.; Prüfer, K.; Kelso, J.; Burbano, H.A.; Pääbo, S.; Meyer, M. 2017. Neandertal and Denisovan DNA from Pleistocene sediments. Science. 356(6338):605-608


Rosas, A.; Ríos, L.; Estalrrich, A.; Liversidge, H.; García-Tabernero, A.; Huguet, R.; Cardoso, H.; Bastir, M.; Lalueza-Fox, C.; de la Rasilla & M.; Dean, C. The growth pattern of Neandertals, reconstructed from a juvenile skeleton from El Sidrón (Spain) Science, 2017 Vol. 357, Issue 6357, pp. 1282-1287
DOI: 10.1126/science.aan6463


Lipson, M.; Szécsényi-Nagy, A.; Mallick, S.; Stégmár, B.; Keerl, V.; Rohland, N.; Stewardson, K.; Ferry, M.; Michael, M.; Oppenheimer, J.; Broomandkhoshbacht, N.; Harney, E.; Nordenfelt, S.; Llamas, B.; Mende, B.G.; Köhler, K. [...]; Lalueza-Fox, C.; Haak, W. & Reich, W. Parallel palaeogenomic transects reveal complex genetic history of early European farmers Nature 551, 368–372 (16 November 2017) doi:10.1038/nature24476

Gelabert, P.; Olalde, O.; de-Dios, T.; Civit, S.; and Lalueza-Fox, C. 2017. Malaria was a weak selective force in ancient EuropeansScientific Reports 7: 1377