The research carried out by this lab aims at understanding the mechanisms that regulate insect oogenesis. The model used is Blattella germanica, an insect with a panoistic ovary type, which is the most primitive ovary type among insects. This lab studies the expression of the genes involved in the main signalling pathways and its regulation by hormones and by the small non-coding RNA that modulates them. The comparison of these results with those already described in other, more modified insect species, suggests that some functions are preserved in evolution, although the regulation of these functions could have changed.
Lab website: Insect Reproduction Lab
Ylla, G; Piulachs, M.D; Belles, X. 2018. Clues about the evolution of insect metamorphosis revealed by comparative transcriptomics of hemimetabolan and holometabolan species. iScience (Cell Press). 4:164–179 doi: 10.1016/j.isci.2018.05.017.
Rubio, M.; Maestro, J.L., Piulachs, M.D.; Belles, X. (2018) Conserved association of Argonaute 1 and 2 proteins with miRNA and siRNA pathways throughout insect evolution, from cockroaches to flies. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1861(6):554-560 doi: 10.1016/j.bbagrm.2018.04.001
Llonga N.; Ylla G.; Bau J.; Belles X.; Piulachs M.-D. 2018. Diversity of piRNA expression patterns during the ontogeny of the German cockroach. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution. 330(5):288-295 doi: 10.1002/jez.b.22815
Harrison, M.C.; Jongepier, E.; Robertson, H.M.; Arning, N.; Bitard-Feildel, T.; Chao, H.; Childers, C.P.; Dinh, H.; Doddapaneni, H.; Dugan, S.; Gowin, J.; Greiner, C.; Han, Y.; Hu, H.; Hughes, D.S.T.; Huylmans, A.K.; Kemena, C.; Kremer, L.P.M.; Lee, S.L.; Lopez-Ezquerra, A.; Mallet, L.; Monroy-Kuhn, J.M.; Moser, A.; Murali, S.C.; Muzny, D.M.; Otani, S.; Piulachs, M.D.; Poelchau, M.; Qu, J.; Schaub, F.; Wada-Katsumata, A.; Worley, K.C.; Xie, Q.; Ylla, G.; Poulsen, M.; Gibbs, R.A.; Schal, C.; Richards, S.; Belles, X.; Korb, J.; Bornberg-Bauer, E. 2018. Hemimetabolous genomes reveal molecular basis of termite eusociality. Nature Ecology and Evolution. 2(3):557-566 doi: 10.1038/s41559-017-0459-1