The research carried out by this lab aims at understanding the mechanisms that regulate insect oogenesis. The model used is Blattella germanica, an insect with a panoistic ovary type, which is the most primitive ovary type among insects. This lab studies the expression of the genes involved in the main signalling pathways and its regulation by hormones and by the small non-coding RNA that modulates them. The comparison of these results with those already described in other, more modified insect species, suggests that some functions are preserved in evolution, although the regulation of these functions could have changed.
Lab website: Insect Reproduction Lab
Patiño-Navarrete, R.; Piulachs, M.D.; Belles, X.; Moya, A.; Latorre, A.; and Peretó, J. 2014. The cockroach Blattella germanica obtains nitrogen from uric acid through a metabolic pathway shared with its bacterial endosymbiont. Biology Letters 10 (7)
Irles, P.; and Piulachs, M.D. 2014. Unlike in Drosophila Meroistic Ovaries, Hippo Represses Notch in Blattella germanica Panoistic Ovaries, Triggering the Mitosis-Endocycle Switch in the Follicular Cells. Plos One 9(11): e113850.
Herraiz, A.; Belles, X.; and Piulachs, M.D. 2014. Chorion formation in panoistic ovaries requires windei and trimethylation of histone 3 lysine 9. Experimental Cell Research 320 (1):46-53.
Irles, P.; Silva-Torres, F. A.; Piulachs, M-D. 2013. RNAi reveals the key role of Nervana 1 in cockroach oogenesis and embryo development. Insect Biochemistry and Molecular Biology 43(2): 178-188