The object of study of the research group are the mechanisms that regulate the metamorphosis of insects , and how these mechanisms have evolved from ancestral species, with a gradual metamorphosis (like in cockroaches or locusts), to the most modified species, with a discontinuous metamorphosis (like in butterflies or flies). Therefore, the questions that the research group on the Evolution of insect metamorphosis seek to answer are: How did metamorphosis develop in insects? What endocrine and molecular mechanisms led to the evolutionary transition from gradual to discontinuous metamorphosis?

Lab website: Bellés Lab


Principal Investigator Principal Investigator

Current members Current members

Ongoing projects Ongoing projects

Publications Publications

Bellés, X. 2017. MicroRNAs and the Evolution of Insect Metamorphosis. Annual review of entomology 62:111-25

Ylla, G.; Fromm, B.; Piulachs, M.D.; and Belles, X. 2016. The microRNA toolkit of insects. Scientific Reports 6:37736. doi: 10.1038/srep37736

Santos, C.G.; Fernandez-Nicolas, A.; and Belles, X. 2016. Smads and insect hemimetabolan metamorphosisDevelopmental Biology 417(1):104-13

Fernández-Nicolás, A.; and Bellés, X. (2016). CREB-binding protein contributes to the regulation of endocrine and developmental pathways in insect hemimetabolan pre-metamorphosisBiochimica et Biophysica Acta 1860: 508–515