The object of study of the research group are the mechanisms that regulate the metamorphosis of insects , and how these mechanisms have evolved from ancestral species, with a gradual metamorphosis (like in cockroaches or locusts), to the most modified species, with a discontinuous metamorphosis (like in butterflies or flies). Therefore, the questions that the research group on the Evolution of insect metamorphosis seek to answer are: How did metamorphosis develop in insects? What endocrine and molecular mechanisms led to the evolutionary transition from gradual to discontinuous metamorphosis?
Lab website: Bellés Lab
Lozano, J.; Kayukawa, T.; Shinoda, T.; and Belles, X. 2014. A Role for Taiman in Insect Metamorphosis. PLoS Genetics 10(10): e1004769.
Herraiz, A.; Belles, X.; and Piulachs, M.D. 2014. Chorion formation in panoistic ovaries requires windei and trimethylation of histone 3 lysine 9. Experimental Cell Research 320 (1):46-53.
Bellès, X.; Santos, C.G. 2014. The MEKRE93 (Methoprene tolerant-Krüppel homolog 1-E93) pathway in the regulation of insect metamorphosis, and the homology of the pupal stage. Insect Biochemistry and Molecular Biology. 52 (0):60-68
Rubio, M.; Montañez, R.; Perez, LidiaMilan, M.; Belles, X. 2013. Regulation of atrophin by both strands of the mir-8 precursor. Insect Biochemistry and Molecular Biology. 43 (11):1009-1014