The object of study of the research group are the mechanisms that regulate the metamorphosis of insects , and how these mechanisms have evolved from ancestral species, with a gradual metamorphosis (like in cockroaches or locusts), to the most modified species, with a discontinuous metamorphosis (like in butterflies or flies). Therefore, the questions that the research group on the Evolution of insect metamorphosis seek to answer are: How did metamorphosis develop in insects? What endocrine and molecular mechanisms led to the evolutionary transition from gradual to discontinuous metamorphosis?

Lab website: Bellés Lab

 

Principal Investigator Principal Investigator

Current members Current members

Ongoing projects Ongoing projects

Publications Publications

Huang, J.-H.;  Lozano, J.; Belles, X. 2013. Broad-complex functions in postembryonic development of the cockroach Blattella germanica shed new light on the evolution of insect metamorphosis. Biochimica et Biophysica Acta (BBA) - General Subjects 1830(1): 2178-2187

Garbutt, J.S.;  Bellés, X.; Richards, E. H.; Reynolds, S. E. 2013. Persistence of double-stranded RNA in insect hemolymph as a potential determiner of RNA interference success: Evidence from Manduca sexta and Blattella germanicaJournal of Insect Physiology. 59 (2):171-8.


Rubio, M.; de Horna, A.; Bellés, X.  2012. MicroRNAs in metamorphic and non-metamorphic transitions in hemimetabolan insect metamorphosis. BMC Genomics 13: 386. doi: 10.1186/1471-2164-13-386.

Mané-Padrós, D.; Borr.s-Castells, F.; Bellés, X.; Martín, D.  2012. Nuclear receptor HR4 plays an essential role in the ecdysteroid-triggered gene cascade in the development of the hemimetabolous insect Blattella germanica. Molecular and Cellular Endocrinology 348: 322-330.

Lozano, J.; Gómez-Orte, E.; Lee, H.J.; Bellés, X.  2012. Super-induction of Dicer-2 expression by alien double-stranded RNAs. An evolutionary ancient response to viral infection? Development, Genes and Evolution 222: 229-235.